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Peroxin

From Wikipedia, the free encyclopedia
Peroxin
Identifiers
SymbolPEX-2,10,12
Membranome190
Peroxin 11
Identifiers
SymbolPEX-11
PfamPF05648
InterProIPR008733
Membranome191
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
Peroxin 13
Identifiers
SymbolPEX-13
PfamPF04088
InterProIPR007223
Membranome192
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
Peroxin 14
Identifiers
SymbolPEX-14
InterProIPR025655
Membranome468

Peroxins (or peroxisomal/peroxisome biogenesis factors) represent several protein families found in peroxisomes.[1] Deficiencies are associated with several peroxisomal disorders. Peroxins serve several functions including the recognition of cytoplasmic proteins that contain peroxisomal targeting signals (PTS) that tag them for transport by peroxisomal proteins to the peroxisome. Peroxins are structurally diverse and have been classified to different protein families. Some of them were predicted to be single-pass transmembrane proteins, for example Peroxisomal biogenesis factor 11.

Genes

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References

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  1. ^ Crookes WJ, Olsen LJ (February 1999). "Peroxin puzzles and folded freight: peroxisomal protein import in review". Die Naturwissenschaften. 86 (2): 51–61. Bibcode:1999NW.....86...51C. doi:10.1007/s001140050572. hdl:2027.42/41882. PMID 10084148. S2CID 22119827.