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MIER1

From Wikipedia, the free encyclopedia
MIER1
Identifiers
AliasesMIER1, ER1, MI-ER1, MIER1 transcriptional regulator
External IDsOMIM: 616848; MGI: 1918398; HomoloGene: 136176; GeneCards: MIER1; OMA:MIER1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001039081
NM_001286221
NM_001286222
NM_001286223
NM_027696

RefSeq (protein)
Location (UCSC)Chr 1: 66.92 – 66.99 MbChr 4: 102.97 – 103.02 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Mesoderm induction early response protein 1 is a protein that in humans is encoded by the MIER1 gene.[5][6][7]

Interactions

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MIER1 has been shown to interact with HDAC1.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000198160Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028522Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Paterno GD, Ding Z, Lew YY, Nash GW, Mercer FC, Gillespie LL (Jul 2002). "Genomic organization of the human mi-er1 gene and characterization of alternatively spliced isoforms: regulated use of a facultative intron determines subcellular localization". Gene. 295 (1): 79–88. doi:10.1016/S0378-1119(02)00823-5. PMID 12242014.
  6. ^ a b Ding Z, Gillespie LL, Paterno GD (Jan 2003). "Human MI-ER1 alpha and beta function as transcriptional repressors by recruitment of histone deacetylase 1 to their conserved ELM2 domain". Molecular and Cellular Biology. 23 (1): 250–8. doi:10.1128/MCB.23.1.250-258.2003. PMC 140656. PMID 12482978.
  7. ^ "Entrez Gene: MIER1 mesoderm induction early response 1 homolog (Xenopus laevis)".

Further reading

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