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GCN1L1

From Wikipedia, the free encyclopedia

GCN1
Identifiers
AliasesGCN1, GCN1L, PRIC295, GCN1L1, eIF2 alpha kinase activator homolog, GCN1 activator of EIF2AK4
External IDsOMIM: 605614; MGI: 2444248; HomoloGene: 5887; GeneCards: GCN1; OMA:GCN1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006836

NM_172719

RefSeq (protein)

NP_006827

NP_766307

Location (UCSC)Chr 12: 120.13 – 120.19 MbChr 5: 115.7 – 115.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Translational activator GCN1 is a protein that in humans is encoded by the GCN1L1 gene.[5][6]

Interactions

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GCN1L1 has been shown to interact with CDC5L.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000089154Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041638Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Marton MJ, Vazquez de Aldana CR, Qiu H, Chakraburtty K, Hinnebusch AG (August 1997). "Evidence that GCN1 and GCN20, translational regulators of GCN4, function on elongating ribosomes in activation of eIF2alpha kinase GCN2". Mol Cell Biol. 17 (8): 4474–89. doi:10.1128/mcb.17.8.4474. PMC 232301. PMID 9234705.
  6. ^ "Entrez Gene: GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)".
  7. ^ Ajuh P, Kuster B, Panov K, Zomerdijk J C, Mann M, Lamond A I (December 2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. 19 (23). ENGLAND: 6569–81. doi:10.1093/emboj/19.23.6569. ISSN 0261-4189. PMC 305846. PMID 11101529.

Further reading

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