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DHRS7

From Wikipedia, the free encyclopedia

DHRS7
Identifiers
AliasesDHRS7, SDR34C1, retDSR4, retSDR4, CGI-86, dehydrogenase/reductase (SDR family) member 7, dehydrogenase/reductase 7
External IDsOMIM: 612833; MGI: 1913625; HomoloGene: 9350; GeneCards: DHRS7; OMA:DHRS7 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016029
NM_001322280
NM_001322281
NM_001322282

NM_025522

RefSeq (protein)

NP_001309209
NP_001309210
NP_001309211
NP_057113

NP_079798

Location (UCSC)Chr 14: 60.14 – 60.17 MbChr 12: 72.7 – 72.71 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Dehydrogenase/reductase (SDR family) member 7 is a protein that in humans is encoded by the DHRS7 gene.[5]

Function

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Short-chain dehydrogenases/reductases (SDRs), such as DHRS7, catalyze the oxidation/reduction of a wide range of substrates, including retinoids and steroids.[6][7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000100612Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021094Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Dehydrogenase/reductase (SDR family) member 7". Retrieved 2014-04-28.
  6. ^ Araya S, Kratschmar DV, Tsachaki M, Stücheli S, Beck KR, Odermatt A (July 2017). "DHRS7 (SDR34C1) – A new player in the regulation of androgen receptor function by inactivation of 5α-dihydrotestosterone?". The Journal of Steroid Biochemistry and Molecular Biology. 171: 288–295. doi:10.1016/j.jsbmb.2017.04.013. PMID 28457967. S2CID 30060280.
  7. ^ Štambergová H, Zemanová L, Lundová T, Malčeková B, Skarka A, Šaft M, Wsól V (January 2016). "Human DHRS7, promising enzyme in metabolism of steroids and retinoids?". Journal of Steroid Biochemistry and Molecular Biology. 155, Part A (Pt A): 112–119. doi:10.1016/j.jsbmb.2015.09.041. PMID 26466768. S2CID 25848948.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.