DescriptionType IV Pilus Twitching Motility Steps.svg
English: Twitching Motility Steps
Pre-PilA is made in the cytoplasm and moves into the inner membrane.
Pre-PilA is inserted into the inner membrane.
PilD, a peptidase, removes a leader sequence, thus making the Pre-Pila shorter and into PilA, the main building-block protein of Pili.
PilF, a NTP-Binding protein that provides energy for Type IV Pili Assembly.
The secretin protein, PilQ, found on the outer membrane of the cell is necessary for the development/extension of the pilus. PilC is the first proteins to form the pilus and are responsible for overall attachment of the pilus.
Once the Type IV Pilus attaches or interacts with what it needs to, it begins to retract. This occurs with the PilT beginning to degrade the last parts of the PilA in the pilus. The mechanism of PilT is very similar to PilF.
Degradation of the pilus into the components to be utilized and synthesized into PilA again.
to share – to copy, distribute and transmit the work
to remix – to adapt the work
Under the following conditions:
attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.