The lesional tissue, i.e. dysplastic epithelium, is seen on the left of the image and characterized by nuclear hyperchromatism (i.e. dark purple nuclei), nuclear crowding (i.e. nuclei are bunched-up), elliptical/cigar-shaped nuclei and loss of goblet cells/reduction in the number of goblet cells. Normal colonic type epithelium is seen on the right of the image and characterized by small round nuclei and abundant goblet cells.
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{{Information |Description={{en|1=Micrograph of a colorectal tubular adenoma. No high grade dysplasia. H&E Stain. Specimen removed during a colonoscopy. The lesional tissue, i.e. dysplastic epithelium, is seen on the left of the image and characterized b