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Description
English: Enveloped virions of Rift Valley fever virus (RVFV) (~90–110 nm in diameter) are characterized by a negative or ambisense RNA genome composed of three single-stranded segments (designated L, M, and S). These three RNA molecules are encapsidated by the nucleoprotein (N), shaping the nucleocapsid which interacts with the viral polymerase (L). Glycoproteins Gn and Gc, expressed by recombinant MVAs, elicit production of virus-neutralizing antibodies. Nonstructural proteins NSm and NSs are expressed during infection.
Date
Source

Calvo-Pinilla, E., Marín-López, A., Moreno, S. et al. A protective bivalent vaccine against Rift Valley fever and bluetongue. npj Vaccines 5, 70 (2020).

https://doi.org/10.1038/s41541-020-00218-y
Author Eva Calvo-Pinilla, Alejandro Marín-López, Sandra Moreno, Gema Lorenzo, Sergio Utrilla-Trigo, Luis Jiménez-Cabello, Julio Benavides, Aitor Nogales, Rafael Blasco, Alejandro Brun, and Javier Ortego

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Captions

Enveloped virions of Rift Valley fever virus (RVFV).

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30 July 2020

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current08:15, 27 January 2021Thumbnail for version as of 08:15, 27 January 2021941 × 966 (681 KB)Guest2625Uploaded a work by Eva Calvo-Pinilla, Alejandro Marín-López, Sandra Moreno, Gema Lorenzo, Sergio Utrilla-Trigo, Luis Jiménez-Cabello, Julio Benavides, Aitor Nogales, Rafael Blasco, Alejandro Brun, and Javier Ortego from Calvo-Pinilla, E., Marín-López, A., Moreno, S. et al. A protective bivalent vaccine against Rift Valley fever and bluetongue. npj Vaccines 5, 70 (2020). https://doi.org/10.1038/s41541-020-00218-y with UploadWizard

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