English: The ribonuclease H domain from the HIV-1 reverse transcriptase protein. The four active-site carboxylate residues are shown in magenta. Two bound manganese ions are shown as purple spheres. A bound inhibitor molecule, beta-thujaplicinol, is shown in green.
Rendered from PDB 3K2P.
Structure of HIV-1 reverse transcriptase with the inhibitor beta-Thujaplicinol bound at the RNase H active site.
Himmel, D.M., Maegley, K.A., Pauly, T.A., Bauman, J.D., Das, K., Dharia, C., Clark, A.D., Ryan, K., Hickey, M.J., Love, R.A., Hughes, S.H., Bergqvist, S., Arnold, E.
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